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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract The purpose of this study is to discuss the effect of COVID-19 on the central nervous system (CNS). Databases were searched for relevant articles. Very little information is currently available. However, two studies provide documented data. The involvement of the central nervous system in COVOID-19 infections is largely unexplored and understudied. However, it is very likely that there is neurological involvement in severe patients. Introduction Coronavirus primarily targets th...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractMucosal barrier immunity in the intestine is essential for maintaining the commensal microflora (friendly gut bacteria) and fighting bacterial infection. Previously, immune and epithelial cells were thought to maintain this balance between harboring the commensal microflora and fighting infection. In this study, the researchers show that the enteric nervous system (ENS), or neurons in the gastrointestinal tract, plays an important role in this balance. The researchers found that the ENS ...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractDrosophila is a genus of flies that is commonly used as a model organism to study a variety of biological processes. The eyeless gene in Drosophila encodes a transcription factor. It is homologous (has a similar structure) to the Pax-6 gene and Aniridia gene in mice and humans respectively. Aniridia, Pax-6, and eyeless are all expressed during eye development. Loss-of-function mutations in these genes result in eye structures becoming smaller or being lost all together, suggesting that t...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    IntroductionEven though more than six million people worldwide are in need of an organ transplant, only about 150,000 people get transplants in a year. One third of the patients who need an organ in the US get one per year. 7,600 people die each year on the organ transplant waiting list.Many individuals in the health care world have concerns about organ donation and transplantation during the COVID-19 pandemic. Patients receiving the organs may be more likely to get an infection or virus. The ne...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractAcute respiratory distress syndrome (ARDS) occurs when inflammation of the lungs leads to respiratory failure without cardiac failure. The mortality of patients with ARDS is still high despite efforts to develop treatments. Identifying biomarkers of ARDS will help decrease mortality. This study looks at soluble advanced glycation end-products, soluble tumor necrosis factor-receptor 1, interleukin-6, interleukin8, and plasminogen activator inhibitor-1 for ARDS treatment by a soluble inhib...
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    dcyphr-d by Michael Rogan on 2020-06-18
    AbstractDiabetes patients seem to have different clinical outcomes based on their race. Understanding how cultural and racial factors affect these patients can bring about more efficient and humane care. It is possible that factors like food/housing insecurity, perceived discrimination, and mental health are not taken into consideration when caring for these patients. More research is necessary to determine how these conditions affect these patients in a clinical setting.Burden of Type 2 Diabete...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractIt is important to understand how non-medical interventions impact COVID-19 transmission, especially to plan future measures to combat the ongoing pandemic. In this study, the researchers used data from American counties of reported infections and deaths along with data about how people move from place to place and a mathematical transmission model. Combining these three things, the researchers quantified changes in COVID-19 transmission in the U.S from March 2020 to May 2020. They found...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractIt is important to understand how SARS-CoV-2 infects the cells so that medications and vaccines can be safely developed. This study looks at angiotensin-converting enzyme 2 (ACE2) and Ang 2 receptor-1 (AT1-R). Some treatments involving ACE2 and AT1-R are recombinant ACE2, ACE inhibitors, AR1-R blockers, Ang 1-7 peptides, and Janus kinase-signal transducer inhibitor (JAKinibs).BackgroundSARS-CoV-2 causes a wide range of symptoms and severity. It has a high infectivity and mortality rate. ...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors compared patients with borderline personality disorder (BPD) with a healthy control group about childhood traumatic life events, parental attitudes, family history of mental illness, and birth risk factors. BPD patients reported more severe traumatic events and childhood traumatic experiences (i.e., sexual abuse, violence, separation from parents). Attitudes towards parents were significantly more negative in BPD patients. BPD patients also reported higher rates of mental il...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractAbout 100,000 people in the United States are in need of a kidney transplant, and 400,000 people are on dialysis. This study aims to discover more about the ability to create a transplantable kidney graft. They decellularized a rat, pig, and human kidney in this study, and recellularized the rat kidney with epithelial and endothelial cells. The grafts made urine in the lab setting. Some grafts were transplanted into the rat, and also produced urine after transplantation.IntroductionDialy...