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    dcyphr-d by Sean Small on 2020-06-18
    Abstract Using psychiatric signs or symptoms, symptom severity, diagnoses based on ICD-10, DSM-IV, or the Chinese Classification of Mental Disorders (third edition), quality of life, and employment as outcome variables in this systematic review and meta-analysis, the researchers examined the psychiatric and neuropsychiatric (i.e., delirium) displays of SARS, MERS, and COVID-19. If SARS-CoV-2 follows a similar course to SARS-CoV or MERS, most patients will likely recover without experiencing a ...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractAbout 100,000 people in the United States are in need of a kidney transplant, and 400,000 people are on dialysis. This study aims to discover more about the ability to create a transplantable kidney graft. They decellularized a rat, pig, and human kidney in this study, and recellularized the rat kidney with epithelial and endothelial cells. The grafts made urine in the lab setting. Some grafts were transplanted into the rat, and also produced urine after transplantation.IntroductionDialy...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors compared patients with borderline personality disorder (BPD) with a healthy control group about childhood traumatic life events, parental attitudes, family history of mental illness, and birth risk factors. BPD patients reported more severe traumatic events and childhood traumatic experiences (i.e., sexual abuse, violence, separation from parents). Attitudes towards parents were significantly more negative in BPD patients. BPD patients also reported higher rates of mental il...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractMucosal barrier immunity in the intestine is essential for maintaining the commensal microflora (friendly gut bacteria) and fighting bacterial infection. Previously, immune and epithelial cells were thought to maintain this balance between harboring the commensal microflora and fighting infection. In this study, the researchers show that the enteric nervous system (ENS), or neurons in the gastrointestinal tract, plays an important role in this balance. The researchers found that the ENS ...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractUnderstanding the origin of SARS-CoV-2 is important for drug development, vaccine development, and future virus prevention. This study shows high sequence conservation around the receptor binding motif (RBM) in the Spike gene in human, bat, and pangolin coronaviruses. Understanding the recombination that led to SARS-CoV-2 could explain how new human coronaviruses emerge.IntroductionCOVID-19 has spread since December 2019 and is now a global pandemic declared by the World Health Organizat...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    AbstractMen and women appear to have different susceptibilities to (COVID-19). The S protein found on the surface of coronaviruses allows the virus to attach to the target (host) cell. After the virus is attached to the host, it will signal for a protein that modifies the S protein and allows the coronavirus to enter the cell. With higher levels of androgens (testosterone), the gene that codes for this protein is expressed more. This could explain why men are more susceptible to COVID19. In orde...
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    dcyphr-d by Akaash Saraf on 2020-06-18
    Abstract:Oxidative stress can lead to Alzheimer’s disease (AD), among other disorders. Oxidative stress is when there is a buildup of highly reactive free-radicals in the body. These free-radicals can lead to cell death through apoptosis. Carnosic Acid (CA) is a chemical found in rosemary and sage that can combat oxidative stress in its active form. The active form of CA stimulates the Nrf2/Keap1 pathway. The Nrf2/Keap1 pathway produces antioxidants which can neutralize the free radicals which, ...
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    dcyphr-d by Sean Small on 2020-06-18
    AbstractThe study sought to clarify the role of boldness in defining psychopathy and distinguish psychopathy from antisocial personality disorder (ASPD).  They used the triarchic model of psychopathy, which describes the disorder along the dimensions of disinhibition, meanness, and boldness, to achieve this. This study evaluated the degree to which aspects of the triarchic model are represented in the Psychopathy Checklist-Revised (PCL-R), in comparison with antisocial personality disorder (ASPD...
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    dcyphr-d by Michael Rogan on 2020-06-18
    AbstractThe very contagious COVID-19 has had an immense impact on the world and killed an unprecedented amount of people across the globe. This especially applies to ethnic and racial minorities. Many minority groups have already been pushed into a societally disadvantaged position, making them even more vulnerable to the COVID-19 pandemic. In the United States, this especially applies to Black Americans. For example, the idea of “Black Immunity” gives some Black Americans the false idea that CO...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The purpose of this article is to investigate the effects of ACEI/ARB on COVID-19 patients. Theoretically, ACEI/ARB should help COVID-19 patients similarly to SARS-CoV patients, but many major cardiology scientific associations have denied this. This study concludes that an association between ACEI/ARB and positive effects on COVID-19 patients is not supported. This may change in the future, however. IntroductionSARS-CoV-2 is similar to SARS-CoV and MERS. Studies show the virus binding ...