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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractDrosophila is a genus of flies that is commonly used as a model organism to study a variety of biological processes. The eyeless gene in Drosophila encodes a transcription factor. It is homologous (has a similar structure) to the Pax-6 gene and Aniridia gene in mice and humans respectively. Aniridia, Pax-6, and eyeless are all expressed during eye development. Loss-of-function mutations in these genes result in eye structures becoming smaller or being lost all together, suggesting that t...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractIn this study, the researchers wanted to understand if there were differences in the placentas of pregnant women with and without COVID-19. They identified pregnant women with COVID-19 and examined their placentas. The researchers compared these placentas with controls and with placentas of women with a history of melanoma (skin cancer). They found that placentas of women with COVID-19 were more likely to show signs of maternal vascular malperfusion (MVM), a form of placental injury rela...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    Abstract3D tissue scaffolds make better models for research and clinical use. In this study, the researchers decellularized apple slices. They grow NIH3T3 fibroblasts, mouse C2C12 muscle myoblasts, and human HeLa epithelial cells into the scaffolds. The cells can grow and live for over 12 weeks. The cells were as dense as other popular scaffold materials. Since apples are cheap and renewable, this may be a great option for scaffolding.Introduction2D cell cultures are not as good of a model for r...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis study aims to see how nonpharmaceutical interventions impacted the 1918-1919 influenza pandemic in 43 US cities. They looked at the excess death rate compared to different interventions taken. The cities that took quick and consistent interventions had the least excess deaths. Those who layered different types of interventions also had lower excess deaths. We can use this data to help plan effective nonpharmaceutical interventions in addition to developing pharmaceutical interventio...
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    dcyphr-d by Adit Seth on 2020-06-18
    Abstract   The purpose of the research is to test whether cognitive psychology is relatively immune to nonnaïveté effects. 9 out of 9 major findings (selected on the basis of three findings per domains of perception/action, memory, and language) of cognitive psychology were reproducible and remained robust. Aims   The paper aims to evaluate whether the “comparatively robust” field of cognitive psychology can hold up to the ‘hallmark of scientific rigour’ by testing the reproducibility of nine pr...
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    dcyphr-d by Sean Small on 2020-06-18
    AbstractUsing a structured interview on an ethnically diverse sample of 394 adolescents from 2 outpatient settings, the authors tested the relationship between reported histories of childhood maltreatment, symptoms of drug (mainly alcohol) abuse and dependence, and risky sexual behavior. They found symptoms of alcohol abuse and dependence mediated relations between scores of (1) emotional neglect (2) sex with co-occurring alcohol use and (3) sexual abuse with sex with co-occurring alcohol abuse....
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors reviewed the gene-environment interactions (GxE) and epigenetic factors in borderline personality disorder (BPD), mainly, as well as avoidant, schizotypal, and antisocial personality disorders. Childhood sexual and physical abuse were found to mediate the expression of susceptibility genes in borderline personality disorder. Epigenetic (i.e., environmental) alterations to brain development and genes involved with stress were found to explain the relationship between BPD and...
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    dcyphr-d by Michael Rogan on 2020-06-18
    Abstract   COVID-19 is also known as SARS-CoV-2 and 2019-nCoV. This coronavirus can cause mild to severe upper respiratory disease, including pneumonia, acute respiratory distress, and death. For some reason children, babies, and adolescents have not contracted the disease as much as other adults. Aims   The author of this paper looks to provide an overview of COVID-19, its origins, and those it infects. The paper discusses knowledge related to the infection of children and infants.Introduction ...
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    dcyphr-d by Michael Rogan on 2020-06-18
    AbstractScientists consider the process of long-term potentiation (LTP) as one of the main things controlling memory formation. LTP takes two neurons that fire together and strengthens the relationship between them. Evidence shows that transcription factor CREB causes changes in the cell. This makes that neuron’s synapse more reactive. It is unclear if CREB and LTP happen together or are separate processes.IntroductionThe Role of the Transcription Factor CREB in Memory           Interest in CREB...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis study aims to see changes in protein expression in NIH 3T3 cells treated with virgin coconut oil (VCO) and hydrolysed virgin coconut oil (HVCO). The cells were treated with either nothing, VCO, or HVCO. Then each of those conditions were analysed to look for changes of expression in MMP-9, PDGF-BB, or TGF-beta1. Both VCO and HVCO increased the expression of all three proteins tested, with HVCO increasing the values by a higher factor. This data tells us that coconut oil is active in...