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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractDrosophila is a genus of flies that is commonly used as a model organism to study a variety of biological processes. The eyeless gene in Drosophila encodes a transcription factor. It is homologous (has a similar structure) to the Pax-6 gene and Aniridia gene in mice and humans respectively. Aniridia, Pax-6, and eyeless are all expressed during eye development. Loss-of-function mutations in these genes result in eye structures becoming smaller or being lost all together, suggesting that t...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractIn this study, the researchers wanted to understand if there were differences in the placentas of pregnant women with and without COVID-19. They identified pregnant women with COVID-19 and examined their placentas. The researchers compared these placentas with controls and with placentas of women with a history of melanoma (skin cancer). They found that placentas of women with COVID-19 were more likely to show signs of maternal vascular malperfusion (MVM), a form of placental injury rela...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis study aims to see how nonpharmaceutical interventions impacted the 1918-1919 influenza pandemic in 43 US cities. They looked at the excess death rate compared to different interventions taken. The cities that took quick and consistent interventions had the least excess deaths. Those who layered different types of interventions also had lower excess deaths. We can use this data to help plan effective nonpharmaceutical interventions in addition to developing pharmaceutical interventio...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors reviewed the gene-environment interactions (GxE) and epigenetic factors in borderline personality disorder (BPD), mainly, as well as avoidant, schizotypal, and antisocial personality disorders. Childhood sexual and physical abuse were found to mediate the expression of susceptibility genes in borderline personality disorder. Epigenetic (i.e., environmental) alterations to brain development and genes involved with stress were found to explain the relationship between BPD and...
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    dcyphr-d by Adit Seth on 2020-06-18
    Abstract   The purpose of the research is to test whether cognitive psychology is relatively immune to nonnaïveté effects. 9 out of 9 major findings (selected on the basis of three findings per domains of perception/action, memory, and language) of cognitive psychology were reproducible and remained robust. Aims   The paper aims to evaluate whether the “comparatively robust” field of cognitive psychology can hold up to the ‘hallmark of scientific rigour’ by testing the reproducibility of nine pr...
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    dcyphr-d by Sean Small on 2020-06-18
    AbstractUsing a structured interview on an ethnically diverse sample of 394 adolescents from 2 outpatient settings, the authors tested the relationship between reported histories of childhood maltreatment, symptoms of drug (mainly alcohol) abuse and dependence, and risky sexual behavior. They found symptoms of alcohol abuse and dependence mediated relations between scores of (1) emotional neglect (2) sex with co-occurring alcohol use and (3) sexual abuse with sex with co-occurring alcohol abuse....
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    dcyphr-d by Michael Rogan on 2020-06-18
    Abstract   COVID-19 is also known as SARS-CoV-2 and 2019-nCoV. This coronavirus can cause mild to severe upper respiratory disease, including pneumonia, acute respiratory distress, and death. For some reason children, babies, and adolescents have not contracted the disease as much as other adults. Aims   The author of this paper looks to provide an overview of COVID-19, its origins, and those it infects. The paper discusses knowledge related to the infection of children and infants.Introduction ...
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    dcyphr-d by Michael Rogan on 2020-06-18
    AbstractScientists consider the process of long-term potentiation (LTP) as one of the main things controlling memory formation. LTP takes two neurons that fire together and strengthens the relationship between them. Evidence shows that transcription factor CREB causes changes in the cell. This makes that neuron’s synapse more reactive. It is unclear if CREB and LTP happen together or are separate processes.IntroductionThe Role of the Transcription Factor CREB in Memory           Interest in CREB...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract Trauma manifests in many behavioral and psychological disturbances in children and adults alike. These manifestations, however, do not always allow for a diagnosis of PTSD by clinicians. Of particular interest are the problems that result from early traumatic experiences with relationships. Such experiences can lead to disturbances in how one interprets social information, defines oneself, emotions, and memory. They can also result in the manifestation of physical symptoms without trace...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractSince COVID-19 clearly affects the respiratory system, the effect of the kidneys has not been well studied. This study looks at the kidneys of 26 COVID-19 patient autopsies. The patients passed away from respiratory failure and multiple organ dysfunction syndrome. 9 of the 26 had kidney injury that increased serum creatine and protein in the urine. The tubules of the kidney showed tissue death, red blood cell clusters, SARS-CoV-2 like clusters, and upregulated ACE2. This study shows dire...