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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract: Respiratory infections such as Coronavirus Disease 2019 (COVID-19) can spread through droplets, airborne particles, and aerosols from speaking, sneezing, or coughing. The spread of the virus can come from presymptomatic, asymptomatic, or symptomatic individuals.The CDC has recommended home-made cloth face coverings for the general public. N95 respirators are the gold standard. Currently they are in short supply and should be reserved for the medical professionals. There is ...
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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe researchers hypothesize that militarization will lead to increased police violence. They studied the 1033 program, which is a U.S. Department of Defense program. It gives excess military equipment to law enforcement agencies (LEA). The researchers looked at the correlation between the amount of equipment transfers and violence. Violence was measured using civilian casualties, change in civilian casualties, and the deaths of dogs. There is a positive and statistically significant corr...
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    dcyphr-d by Sean Small on 2020-06-18
    AbstractThe study sought to clarify the role of boldness in defining psychopathy and distinguish psychopathy from antisocial personality disorder (ASPD).  They used the triarchic model of psychopathy, which describes the disorder along the dimensions of disinhibition, meanness, and boldness, to achieve this. This study evaluated the degree to which aspects of the triarchic model are represented in the Psychopathy Checklist-Revised (PCL-R), in comparison with antisocial personality disorder (ASPD...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis study aims to see how nonpharmaceutical interventions impacted the 1918-1919 influenza pandemic in 43 US cities. They looked at the excess death rate compared to different interventions taken. The cities that took quick and consistent interventions had the least excess deaths. Those who layered different types of interventions also had lower excess deaths. We can use this data to help plan effective nonpharmaceutical interventions in addition to developing pharmaceutical interventio...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    IntroductionThis study aims to discover the tropism of SARS-CoV-2 to other organs. Viral tropism refers to the ability of a virus to infect other cells. SARS-CoV-2 mainly infects the cells of the lungs and respiratory system. The respiratory tropism can explain why we see respiratory symptoms in COVID-19 patients. But, the virus does interact with other organ systems as well. In this study, 27 COVID-19 positive patient autopsies were done to see which other organs SARS-CoV-2 can infect. Most of ...
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    dcyphr-d by David Chen on 2020-06-18
    AbstractThe Pan-Cancer Analysis of Whole Genomes Consortium has identified somatic mutations that represent a profile of characteristic signatures. The size of the curated dataset makes this discovery of mutation signatures the most comprehensive dataset yet. Estimated contributions of characteristic signatures for each cancer type can be associated with causes of cancer that originate in the body or from the environment. Aims The study aims to characterize the contribution of mutations from mul...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    Abstract3D tissue scaffolds make better models for research and clinical use. In this study, the researchers decellularized apple slices. They grow NIH3T3 fibroblasts, mouse C2C12 muscle myoblasts, and human HeLa epithelial cells into the scaffolds. The cells can grow and live for over 12 weeks. The cells were as dense as other popular scaffold materials. Since apples are cheap and renewable, this may be a great option for scaffolding.Introduction2D cell cultures are not as good of a model for r...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractThe transmission of SARS-CoV-2 through droplets is clear, but whether it can be transmitted through aerosols (airborne transmission) is not. This study investigated whether SARS-CoV-2 is transmitted through aerosols by measuring viral RNA in two Wuhan hospitals during the COVID-19 outbreak. The researchers found that levels of SARS-CoV-2 RNA in isolation wards and vented patient rooms was low, but higher in patients' toilet areas. SARS-CoV-2 levels were undetectable except in two areas p...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors reviewed the gene-environment interactions (GxE) and epigenetic factors in borderline personality disorder (BPD), mainly, as well as avoidant, schizotypal, and antisocial personality disorders. Childhood sexual and physical abuse were found to mediate the expression of susceptibility genes in borderline personality disorder. Epigenetic (i.e., environmental) alterations to brain development and genes involved with stress were found to explain the relationship between BPD and...
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    dcyphr-d by David Chen on 2020-06-18
    AbstractThe ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium has systematically documented the variation in whole genomes associated with cancer across 38 tumour types and 2,658 whole cancer genomes. Most cancer genomes will experience 4 to 5 driver mutations in the whole genome. About 5% of cancer genomes do not have any identified driver mutations, which suggests that research towards cancer driver mutations is incomplete. Both common and rare variants of mutations, such as point mut...