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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractResearchers conducted a phylogenetic analysis of 160 human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes. They found three major variants of the virus: A, B, and C. The A variant represents the ancestral type with the bat coronavirus as the outgroup. The B variant is common in East Asia. But, this variant often mutates when it leaves East Asia. Thus, genetic variation may be lost for the B type of virus outside of Asia. There may also be immunological or environmen...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract: Respiratory infections such as Coronavirus Disease 2019 (COVID-19) can spread through droplets, airborne particles, and aerosols from speaking, sneezing, or coughing. The spread of the virus can come from presymptomatic, asymptomatic, or symptomatic individuals.The CDC has recommended home-made cloth face coverings for the general public. N95 respirators are the gold standard. Currently they are in short supply and should be reserved for the medical professionals. There is ...
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    dcyphr-d by Sean Small on 2020-06-18
    AbstractThe study sought to clarify the role of boldness in defining psychopathy and distinguish psychopathy from antisocial personality disorder (ASPD).  They used the triarchic model of psychopathy, which describes the disorder along the dimensions of disinhibition, meanness, and boldness, to achieve this. This study evaluated the degree to which aspects of the triarchic model are represented in the Psychopathy Checklist-Revised (PCL-R), in comparison with antisocial personality disorder (ASPD...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis study aims to see how nonpharmaceutical interventions impacted the 1918-1919 influenza pandemic in 43 US cities. They looked at the excess death rate compared to different interventions taken. The cities that took quick and consistent interventions had the least excess deaths. Those who layered different types of interventions also had lower excess deaths. We can use this data to help plan effective nonpharmaceutical interventions in addition to developing pharmaceutical interventio...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    IntroductionThis study aims to discover the tropism of SARS-CoV-2 to other organs. Viral tropism refers to the ability of a virus to infect other cells. SARS-CoV-2 mainly infects the cells of the lungs and respiratory system. The respiratory tropism can explain why we see respiratory symptoms in COVID-19 patients. But, the virus does interact with other organ systems as well. In this study, 27 COVID-19 positive patient autopsies were done to see which other organs SARS-CoV-2 can infect. Most of ...
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    dcyphr-d by David Chen on 2020-06-18
    AbstractThe Pan-Cancer Analysis of Whole Genomes Consortium has identified somatic mutations that represent a profile of characteristic signatures. The size of the curated dataset makes this discovery of mutation signatures the most comprehensive dataset yet. Estimated contributions of characteristic signatures for each cancer type can be associated with causes of cancer that originate in the body or from the environment. Aims The study aims to characterize the contribution of mutations from mul...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract Much research on COVID-19 is needed to understand its nature (i.e., how it spreads) and to come up with more targets for vaccines and medication. This study discusses what is currently known about the structure and qualities of SARS-CoV-2, including how it spreads and where it comes from.  IntroductionSARS-CoV-2 belongs to the Betacoronavirus (β-CoVs) genera of the Orthocoronavirinae subfamily, making it known to infect mammals and similar to the previous SARS-CoV and MERS-CoV. COVID-19...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractThe transmission of SARS-CoV-2 through droplets is clear, but whether it can be transmitted through aerosols (airborne transmission) is not. This study investigated whether SARS-CoV-2 is transmitted through aerosols by measuring viral RNA in two Wuhan hospitals during the COVID-19 outbreak. The researchers found that levels of SARS-CoV-2 RNA in isolation wards and vented patient rooms was low, but higher in patients' toilet areas. SARS-CoV-2 levels were undetectable except in two areas p...
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    dcyphr-d by Sean Small on 2020-06-18
    Abstract The authors reviewed the gene-environment interactions (GxE) and epigenetic factors in borderline personality disorder (BPD), mainly, as well as avoidant, schizotypal, and antisocial personality disorders. Childhood sexual and physical abuse were found to mediate the expression of susceptibility genes in borderline personality disorder. Epigenetic (i.e., environmental) alterations to brain development and genes involved with stress were found to explain the relationship between BPD and...
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    dcyphr-d by Janet Hsu on 2020-06-18
    Abstract The researchers have developed a machine learning model called the Stability of Planetary Orbital Configurations Klassifier (SPOCK). This model can characterize thousands of planetary systems at once. SPOCK is much quicker and more efficient than former models. The former models based predictions off of angular momentum deficit and chaos. Researchers input the eccentricity of planet orbits, radial velocity, and transit duration into SPOCK. Then, SPOCK can predict how stable the planetar...