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dcyphr | COVID-19
COVID-19

Cutting edge research about the disease caused by a coronavirus called SARS-CoV-2.

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    dcyphr-d by Janet Hsu on 2020-06-18
    Abstract Black American communities are suffering tremendously from the COVID-19 pandemic. Underlying health and social problems make the issues from the pandemic worse. The syndemic theory can help to understand what is happening. A syndemic is when multiple diseases concentrate in a particular community. The co-occurence of the diseases worsen the outcomes of the diseases. The syndemic often coincides with the social problems of that community. Social factors and history have especially caused...
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    dcyphr-d by Michael Rogan on 2020-06-18
    Abstract   Coronaviruses are a group of viruses that cause severe respiratory symptoms. Lipid membranes envelop the viral RNA. Viruses enter the cell through the endocytic pathway. Controlling this pathway has potential for developing treatments against coronaviruses. Aims    The author writes to compare data that looks into the effectiveness of controlling the endocytic pathway as a treatment for coronaviruses. The author also presents possible treatments. Introduction      Autophagy and the En...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractBased on genetics, SARS-CoV-2 is similar to SARS-related coronaviruses seen in horseshoe bats. This study tests small live tissue samples, called organoids, in horseshoe bats. The organoids in this study were made to mimic the intestines. These organoids can be infected with SARS-CoV-2. This shows that COVID-19 can affect the digestive system, not the respiratory system alone. This study compared stool samples and intestinal organoids from bats and humans, and found live virus in both. T...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    SummaryIn the past month, there was an outbreak of Kawasaki disease in the Bergamo province. Researchers compared past cases of Kawasaki disease before and after the SARS-CoV-2 pandemic.19 patients had Kawasaki disease from 2015 to Feb 17th 2020. There have been 10 cases of Kawasaki disease from Feb 18th to April 20th, 2020. The rate of Kawasaki disease incidence has increased by 30 times. A similar increased rate is expected in other countries affected by the SARS-CoV-2 outbreak.IntroductionB...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract The outbreak of coronavirus has created concern for transmission from mother to fetus. Databases were searched for all relevant academic articles. A review of 13 final articles published has revealed that COVID-19 can cause fetal distress, miscarriage, respiratory distress, and preterm delivery. However, it does not infect newborns. There is no documented transmission from mother to baby. Pregnant women experience the same symptoms as non-pregnant women. It is important to documen...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis goal of this study is to see if levels of Vitamin D affects case rate and mortality rate of COVID-19 in European countries. It was found that with higher levels of Vitamin D, the case rate and mortality rate were lower.BackgroundIn many other respiratory tract infections, Vitamin D helps to prevent more serious complications. But COVID-19 may be different because the virus interacts with ACE2 to enter the cell. Calcitriol, which is a form of Vitamin D, increases the amount of ACE2. ...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract In this study, the IgM and IgG antibodies associated with SARS-CoV-2 are analyzed from 221 COVID19 positive patients. These antibodies can give insight on the diagnosis, cause of the virus, and course of the virus. The concentration of the IgM antibodies was highest between day 16 and 18 after the first day of symptoms. IgG antibodies peaked between days 19 and 21. The IgG concentration was much higher in severe cases compared to other cases of COVID19. Just over 50% of patients who d...
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    dcyphr-d by Luca Gisellu on 2020-06-18
    Abstract Mandates for public mask use during the COVID-19 pandemic have forced widespread use of homemade masks and mask alternatives due to a shortage of professional supplies. Many homemade masks and recommended alternatives have not been tested for their ability to reduce disease spread. The authors of this paper have created a simple measurement method to see how well certain masks prevent the spread of respiratory droplets while talking. They compared commonly available masks to surgical ma...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    AbstractSince SARS-CoV-2 is thought to have originated from bats, it is of significant importance that we observe the susceptibility of other animals as a potential transmission route. In this study the researchers investigate how susceptible ferrets and other animals that are in close contact with humans are to SARS-CoV-2. The researchers found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks. However ferrets and cats are not as resistant to infection as the other animals st...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract In cell samples grown in a laboratory setting, the antiparasitic medication ivermectin has shown to be effective against SARS-CoV-2. This has peaked interest because it could possibly treat COVID-19. This study looks at the feasibility of ivermectin as a treatment for COVID-19. The dose needed to be effective against COVID-19 is likely too high for humans to use safely. Introduction As the COVID-19 pandemic continues, several possible drugs are being explored as a tre...