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dcyphr | Cell Biology
Cell Biology

Research concerning the structure and function of the fundamental unit of life. Includes articles from Yale BIOL 102 class.

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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe three proteins, Sar1p, Sec13p complex, and Sec23p complex, contribute to the synthesis of transport vesicles. The vesicles derive from the endoplasmic reticulum. Vesicle formation requires GTP. But, GMP-PNP, a nonhydrolyzable analog of GTP, can cause vesicle formation as well. But, GMP-PNP vesicles cannot target and fuse with the Golgi complex. All three proteins remain on the vesicles. Yet, GTP vesicles are functional. Sar1p dissociates from GTP vesicles, allowing for fusion. Thin s...
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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe jellyfish Aequorea victoria expresses green fluorescent protein (GFP). A complementary DNA can be expressed in prokaryotic or eukaryotic cells. Other substrates or cofactors are not necessary for this fluorescence. Thus, GFP can be used to monitor gene expression and protein localization in living organisms.IntroductionIn the jellyfish Aequorea victoria, the green fluorescent protein (GFP) emits a green light. When the photoprotein aequorin binds to calcium, GFP absorbs excitation en...
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    dcyphr-d by Anmol Guard on 2020-06-18
    Abstract Myosin VI is necessary for auditory and vestibular functions in mammals. Genetic mutations of it lead to hearing impairment and vestibular disabilities. This study shows a mutation in the motor in a mouse model, Tailchaser, stops myosin VI from working properly. Myosin VI may not be able to work alongside stereocilia. Author Summary Human deafness is caused by a variety of genes in different people. Mutations in five Myosins are known to cause hearing issues. Myosins...
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    dcyphr-d by Christina Hijiya on 2020-06-18
    AbstractThe symbiosis, or mutually beneficial relationship between organisms, between the Hawaiian bobtail squid and bioluminescent bacteria Vibrio fischeri gives researchers an opportunity to study and understand interactions between microorganisms and their hosts in a natural environment. V. fischeri colonizes a specialized organ in the bobtail squid meant for producing light (light organ). This begins a lifelong symbiosis in which each morning, the squid expels 95% of the bacteria and other ...